Stuart Black Selected Research

3(S)-thiomethyl pyrrolidine

7/2018

MK-8353: Discovery of an Orally Bioavailable Dual Mechanism ERK Inhibitor for Oncology.

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Stuart Black Research Topics

Disease

6	Neoplasms (Cancer) 07/2018 - 04/2002
6	Infections 04/2017 - 09/2014
2	Melanoma (Melanoma, Malignant) 01/2016 - 07/2013
2	Breast Neoplasms (Breast Cancer) 09/2007 - 12/2005
1	Social Phobia 01/2021
1	Fibrosis (Cirrhosis) 01/2017
1	Chronic Hepatitis C 01/2017
1	Hepatitis C 01/2015
1	Reinfection 12/2014
1	Carcinogenesis 12/2005

Drug/Important Bio-Agent (IBA)

4	grazoprevirIBA 04/2017 - 12/2014
3	elbasvirIBA 04/2017 - 11/2015
3	Ribavirin (Virazole)FDA LinkGeneric 01/2017 - 09/2014
2	InterferonsIBA 01/2017 - 12/2014
2	Peptide Hydrolases (Proteases)FDA Link 01/2017 - 01/2015
2	SCH772984IBA 01/2016 - 07/2013
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2016 - 07/2013
2	N- (3- amino- 1- (cyclobutylmethyl)- 2,3- dioxopropyl)- 3- (2- ((((1,1- dimethylethyl)amino)carbonyl)amino)- 3,3- dimethyl- 1- oxobutyl)- 6,6- dimethyl- 3- azabicyclo(3.1.0)hexan- 2- carboxamideIBA 01/2015 - 09/2014
2	Messenger RNA (mRNA)IBA 04/2006 - 12/2005
1	3(S)-thiomethyl pyrrolidineIBA 07/2018
1	MK-8353IBA 07/2018
1	TabletsIBA 01/2017
1	Pharmaceutical PreparationsIBA 01/2015
1	Mitogen-Activated Protein KinasesIBA 07/2013
1	Tamoxifen FDA LinkGeneric 09/2007
1	Hormones (Hormone)IBA 09/2007
1	Aromatase (CYP19)IBA 09/2007
1	Anastrozole (Arimidex)FDA LinkGeneric 09/2007
1	lonafarnib (SCH 66336)IBA 09/2007
1	Estrogen Receptor Modulators (Antiestrogen)IBA 09/2007
1	Aromatase InhibitorsIBA 09/2007
1	Farnesyltranstransferase (Farnesyltransferase)IBA 09/2007
1	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 04/2006
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 04/2006
1	LigandsIBA 04/2006
1	Proteins (Proteins, Gene)FDA Link 12/2005
1	Purinergic P1 Receptors (Adenosine Receptor)IBA 12/2005
1	Small Interfering RNA (siRNA)IBA 12/2005
1	ThymidineIBA 12/2005
1	Inhibitor of Apoptosis ProteinsIBA 04/2002
1	SurvivinIBA 04/2002

Therapy/Procedure

2	Therapeutics 07/2018 - 01/2016
1	Neurofeedback 01/2021